Generic Epinephrine Auto-Injector Now Available: Important Note about Prescribing

CVS recently announced that it will offer a generic version of Adrenaclick (epinephrine auto-injector) at a cash price of $110 per two-pack, which is substantially less expensive than Mylan’s generic version of EpiPen priced at $339 per two-pack. Depending on the plan, patients with insurance may have a copay as low as $5 for the generic Adrenaclick. A $100 pharmacy discount coupon is also available to bring the cost down to as little as $10.

Prescribers who want their patients to have access to the lowest-cost generic version will need to write the prescription for “epinephrine auto-injector” rather than naming any particular brand. For patients who already have an existing prescription for EpiPen, a change to their prescription is required in order to switch to lowest-cost generic version. Pharmacists cannot substitute to the generic version of Adrenaclick because the FDA doesn’t consider the device to be therapeutically equivalent to the EpiPen.

When switching patients to a different epinephrine product, make sure they know how to properly administer the drug as directions vary between injectors. Their pharmacy can provide training and even retraining if several months have passed since they were last instructed. Training can help prevent a delay in treatment or injury during an emergency situation.